A Visible and Near-Infrared Light Activatable Diazocoumarin Probe for Fluorogenic Protein Labeling in Living Cells

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A highly selective near-infrared fluorescent probe for imaging H2Se in living cells and in vivo.

Hydrogen selenide (H2Se), a highly reactive Se species, is an important selenium metabolism intermediate involved in many physiological and pathological processes. This compound is of scientific interest with regard to the real-time monitoring of H2Se in living cells and in vivo to understand the anti-cancer mechanism of selenium. However, monitoring H2Se in living cells is still challenging du...

متن کامل

An intracellularly activatable, fluorogenic probe for cancer imaging.

A newly designed, dual-functional probe based on intracellular activation has been successfully developed for the detection of cancer cells. The probe is nearly non-fluorescent in buffer due to its highly efficient FRET quenching, but it can be specifically activated with dramatic fluorescence enhancement upon intracellular cathepsin B cleavage in target cancer cells after selective internaliza...

متن کامل

A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells.

A near-infrared fluorescent probe (Cy-O-CHO) for the detection of endogenous Cys/Hcy in living cells was designed and synthesized. Cy-O-CHO exhibited high sensitivity and good selectivity to Cys/Hcy under physiological conditions with a detection limit of 7.9 nM for Cys.

متن کامل

A near-infrared fluorescent probe for monitoring ozone and imaging in living cells.

A near-infrared fluorescent probe (Trp-Cy) for endogenous ozone is presented, which exhibited a large stokes shift about 140 nm and a rapid fluorescence response to ozone with high selectivity and sensitivity.

متن کامل

A near-infrared reversible fluorescent probe for peroxynitrite and imaging of redox cycles in living cells.

BzSe-Cy is a small-molecule fluorescent probe containing Se, which can respond reversibly to changes in ONOO(-) or reduced ascorbate and exhibit high sensitivity and selectivity for ONOO(-).

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of the American Chemical Society

سال: 2020

ISSN: 0002-7863,1520-5126

DOI: 10.1021/jacs.0c08068